SCHEMBL8768129

SCHEMBL8768129

Cc1cc(SCCc2ccc(OC(C)(C)C(=O)O)cc2)c(C)c(C)c1O

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 16/20 0.52
PPARG P37231 13/20 0.48
PPARD Q03181 11/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8925639 0.88 PPARA (0.48) PPARAPPARGPPARD
SCHEMBL8768731 0.78 PPARA (0.62) PPARAPPARGPPARD
SCHEMBL8768773 0.77 PPARA (0.54) PPARAPPARGPPARD
SCHEMBL8617700 0.77 PPARA (0.47) PPARAPPARGPPARD
SCHEMBL9233604 0.76 PPARA (0.42) PPARAPPARGPPARD
SCHEMBL8050813 0.74 PPARA (0.46) PPARAPPARG
SCHEMBL8924670 0.74 FBP1 (0.33) PPARAPPARGPPARD
SCHEMBL8622750 0.72 PPARA (0.51) PPARAPPARGPPARD
SCHEMBL8923120 0.71 PPARA (0.53) PPARAPPARGPPARD
SCHEMBL8767430 0.70 PPARA (0.56) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0621255-B1 Substituted phenoxy-isobutyric acids and esters ADIR (FR) 1997-08-20 EP claimed
US-5627205-A ANTILIPEMIC AGENTS AND ANTIOXIDANTS ADIR ET COMPAGNIE (FR) 1997-05-06 US disclosed