SCHEMBL8768320

SCHEMBL8768320

Fc1cc([C@H]2CC[C@H]([C@H]3CC[C@H](CC4CCCC4)CC3)CC2)cc(F)c1OC(F)F

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8767897 0.92 OPRL1 (0.32) PDE4APDE4BPDE4CPDE4D
SCHEMBL8768286 0.90 SIGMAR1 (0.31) PDE4APDE4BPDE4CPDE4D
SCHEMBL8767240 0.90 OPRL1 (0.31) PDE4APDE4BPDE4CPDE4D
SCHEMBL8766976 0.89 OPRL1 (0.32)
SCHEMBL8766980 0.89 OPRL1 (0.32)
SCHEMBL8766971 0.89 OPRL1 (0.32)
SCHEMBL8768289 0.89
SCHEMBL9153125 0.85 TRPV3 (0.31)
SCHEMBL8767054 0.85 SIGMAR1 (0.33) PDE4APDE4BPDE4CPDE4D
SCHEMBL9153132 0.85 TRPV3 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0789067-A1 Cyclopentyl derivatives useful as liquid crystals Rolic AG (CH) 1997-08-13 EP disclosed