SCHEMBL8768322

SCHEMBL8768322

Cc1nc2ccc(O)c(O)c2c(C)c1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 1/20 0.49
PDE3A Q14432 1/20 0.49
KDM4E B2RXH2 7/20 0.37
ALDH1A1 P00352 5/20 0.37
GAA P10253 2/20 0.37
HPGD P15428 2/20 0.37
STAT3 P40763 1/20 0.37
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
MAPT P10636 5/20 0.33
TP53 P04637 2/20 0.33
LMNA P02545 2/20 0.33
CYP1A2 P05177 2/20 0.33
POLB P06746 1/20 0.33
ALOX15 P16050 1/20 0.33
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PDE10A Q9Y233 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL918406 0.80 MAPT (0.37) KDM4EALDH1A1GAAHPGDSTAT3
SCHEMBL480945 0.76 GAA (0.46) KDM4EALDH1A1GAAHPGDSTAT3
SCHEMBL28030936 0.76 KDM4E (0.37) KDM4EALDH1A1GAAHPGDSTAT3
SCHEMBL5654051 0.74 MAPT (0.42) PDE3BPDE3AKDM4EALDH1A1MAPT
SCHEMBL28427406 0.73 PARP1 (0.33) PDE3BPDE3AKDM4EALDH1A1GAA
SCHEMBL27390917 0.68 PDE3B (0.49) PDE3BPDE3AALDH1A1HPGDLMNA
SCHEMBL2823571 0.68 ALDH1A1 (0.33) PDE3BPDE3AKDM4EALDH1A1GAA
SCHEMBL2823356 0.68 PARP1 (0.36) PDE3BPDE3AKDM4EALDH1A1GAA
SCHEMBL28427197 0.67
SCHEMBL29791541 0.67 ELANE (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114958468-A High-performance cooling lubricant 浙江渤威能源科技有限公司 2022-08-30 CN claimed
CN-114958467-A Environment-friendly cooling preparation for air compressor 浙江渤威能源科技有限公司 2022-08-30 CN claimed
CN-110387089-A A kind of novel heat-conducting ambroin 蚌埠创特新材料科技有限公司 2019-10-29 CN claimed
CN-110092984-A A kind of heat-resistant fireproof ethylene propylene diene rubber 安徽立信橡胶科技有限公司 2019-08-06 CN claimed
EP-0633058-B1 Process for preparing spherules RHONE POULENC NUTRITION ANIMAL (FR) 1997-09-17 EP claimed
EP-0618001-B1 Process for preparing active agents containing spherules RHONE POULENC NUTRITION ANIMAL (FR) 1997-08-13 EP claimed
EP-0633058-A1 Process for preparing spherules RHONE-POULENC NUTRITION ANIMALE (FR) 1995-01-11 EP claimed
EP-0618001-A1 Process for preparing active agents containing spherules RHONE-POULENC NUTRITION ANIMALE (FR) 1994-10-05 EP claimed
CN-114958467-B Environment-friendly cooling preparation for air compressor 浙江渤威能源科技有限公司 2023-03-17 CN disclosed
CN-114369492-B Screw type air compressor oil composition and air compressor oil 北京盛鑫和谐润滑油脂有限公司 2022-11-01 CN disclosed
CN-114958468-A High-performance cooling lubricant 浙江渤威能源科技有限公司 2022-08-30 CN disclosed
CN-114958467-A Environment-friendly cooling preparation for air compressor 浙江渤威能源科技有限公司 2022-08-30 CN disclosed
CN-114958467-A Environment-friendly cooling preparation for air compressor 浙江渤威能源科技有限公司 2022-08-30 CN disclosed
CN-114369492-A Screw type air compressor oil composition and air compressor oil 北京盛鑫和谐润滑油脂有限公司 2022-04-19 CN disclosed
EP-0618001-B1 Process for preparing active agents containing spherules RHONE POULENC NUTRITION ANIMAL (FR) 1997-08-13 EP disclosed
EP-0633058-A1 Process for preparing spherules RHONE-POULENC NUTRITION ANIMALE (FR) 1995-01-11 EP disclosed
EP-0618001-A1 Process for preparing active agents containing spherules RHONE-POULENC NUTRITION ANIMALE (FR) 1994-10-05 EP disclosed
EP-0167239-B1 DC ELECTRIC POWER CABLE FUJIKURA LTD. (JP) 1989-11-23 EP disclosed
US-4366746-A Pressurized hydraulic fluid system using cross-linked chlorinated polyethylene hose AEROQUIP CORPORATION (US) 1983-01-04 US disclosed
US-3962517-A Electric cables BICC LIMITED (EN) 1976-06-08 US disclosed