Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36374 | 0.89 | CES1 (0.48) | CES1MEN1KMT2APTPN1MAPT | |
| Methoxymethane SCHEMBL36098 | 0.83 | CES1 (0.56) | CES1MEN1LMNAKMT2AMAPT | |
| Trifluoromethylbenzene SCHEMBL28170271 | 0.81 | CES1 (0.50) | CES1LMNAPTPN1RAB9ANPC1 | |
| SCHEMBL11057570 | 0.80 | CES1 (0.45) | CES1MEN1LMNAKMT2ARAB9A | |
| Ether SCHEMBL5403863 | 0.79 | CES1 (0.47) | CES1MEN1LMNAKMT2AMAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL503620 | 0.78 | CES1 (0.46) | CES1LMNAPTPN1RAB9ASRC | |
| SCHEMBL8329073 | 0.78 | CES1 (0.46) | CES1LMNAMAPTKDM4EHIF1A | |
| SCHEMBL27612829 | 0.78 | SMN1; SMN2 (0.50) | CES1RAB9AMAPTSRCNPC1 | |
| SCHEMBL11789186 | 0.76 | CES1 (0.50) | CES1MEN1KMT2APTPN1MAPT | |
| SCHEMBL3521742 | 0.76 | CES1 (0.43) | CES1MEN1LMNAKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792146-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1997002028-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-01-23 | — | — | WO | disclosed |