Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768408 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KDM4EPOLBCTSDBACE1 | |
| SCHEMBL21495009 | 0.92 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBCTSDBACE1 | |
| SCHEMBL4802924 | 0.88 | TSHR (0.43) | ALDH1A1SLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL4802917 | 0.88 | TSHR (0.43) | ALDH1A1SLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8768323 | 0.88 | SLC6A4 (0.42) | ALDH1A1KDM4EPOLBCTSDBACE1 | |
| SCHEMBL9062293 | 0.87 | TSHR (0.43) | ALDH1A1SLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL5356249 | 0.87 | TSHR (0.43) | ALDH1A1SLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL5356253 | 0.87 | TSHR (0.43) | ALDH1A1SLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8767584 | 0.87 | CTSD (0.40) | ALDH1A1KDM4EPOLBCTSDBACE1 | |
| SCHEMBL9062289 | 0.87 | TSHR (0.43) | ALDH1A1SLC6A4SLC6A3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |