Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768421 | 1.00 | PGR (0.39) | PGRCYP3A4CYP17A1CYP11B2CYP2C9 | |
| SCHEMBL19850903 | 0.98 | KMT2A (0.39) | PGRCYP3A4CYP17A1CYP11B2CYP2C9 | |
| SCHEMBL14525326 | 0.88 | HSP90AA1 (0.46) | PGRCYP3A4CYP17A1CYP11B2CYP2C9 | |
| SCHEMBL14064159 | 0.87 | ESR2 (0.46) | PGRCYP3A4CYP17A1CYP11B2CYP2C9 | |
| SCHEMBL13345629 | 0.87 | KDM1A (0.35) | PGRCYP3A4CYP17A1CYP11B2CYP2C9 | |
| SCHEMBL8767043 | 0.87 | CYP3A4 (0.36) | CYP3A4CYP2C9APPHSP90AA1GAA | |
| SCHEMBL8767041 | 0.87 | CYP3A4 (0.36) | CYP3A4CYP2C9APPHSP90AA1GAA | |
| SCHEMBL8767567 | 0.86 | HTR2A (0.39) | KMT2AKDM1ANPC1RAB9A | |
| SCHEMBL18857328 | 0.85 | HSP90AA1 (0.39) | CYP3A4CYP2C9APPHSP90AA1GAA | |
| SCHEMBL8024951 | 0.84 | ESR2 (0.42) | PGRCYP3A4CYP17A1CYP11B2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |