Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ASPH | Q12797 | 1/20 | 0.30 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2803444 | 0.79 | CDK2 (0.37) | HCAR2KDM4ELMNA | |
| SCHEMBL10240090 | 0.77 | KDM4C (0.38) | HCAR2KDM4ELMNA | |
| SCHEMBL2801188 | 0.76 | HCAR3 (0.38) | HCAR2KDM4EASPHKDM8 | |
| SCHEMBL2801161 | 0.76 | PGK1 (0.35) | HCAR2KDM4ECYP2C19LMNA | |
| SCHEMBL2801895 | 0.75 | KDM4C (0.51) | KDM4EASPHKDM8LMNA | |
| SCHEMBL2801403 | 0.74 | HSD17B10 (0.38) | KDM4ECYP2C19HSD17B10LMNA | |
| SCHEMBL2802724 | 0.74 | HCAR3 (0.38) | HCAR2KDM4EASPHKDM8 | |
| SCHEMBL15871949 | 0.74 | KDM4E (0.42) | KDM4ELMNA | |
| SCHEMBL2233228 | 0.74 | CD38 (0.41) | KDM4E | |
| SCHEMBL2802551 | 0.73 | HCAR3 (0.41) | HCAR2KDM4EASPHKDM8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792146-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1997002028-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-01-23 | — | — | WO | disclosed |