⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL27670463 | 0.83 | GLRA1 (0.46) | — | |
| SCHEMBL669529 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL9540508 | 0.79 | — | — | |
| SCHEMBL2359598 | 0.78 | — | — | |
| SCHEMBL21636798 | 0.75 | — | — | |
| SCHEMBL4644554 | 0.75 | — | — | |
| SCHEMBL321976 | 0.73 | — | — | |
| SCHEMBL20678765 | 0.71 | — | — | |
| SCHEMBL18808043 | 0.71 | FDPS (0.32) | — | |
| SCHEMBL765962 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8519155-B2 | Choline and tromethamine salt of licofelone | C-A-I-R BIOSCIENCES GMBH (DE) | 2013-08-27 | — | — | US | disclosed |
| US-20120010261-A1 | CHOLINE AND TROMETHAMINE SALT OF LICOFELONE | C-A-I-R BIOSCIENCES GMBH (DE) | 2012-01-12 | — | — | US | disclosed |
| EP-0792146-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1997002028-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-01-23 | — | — | WO | disclosed |
| EP-0365541-B1 | PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES | BRACCO S.p.A. (IT) | 1992-08-12 | — | — | EP | disclosed |
| US-5066823-A | Rearrangement reaction, contrast agent for radiology | BRACCO INDUSTRIA CHEMICA S.P.A. (IT) | 1991-11-19 | — | — | US | disclosed |
| EP-0365541-A1 | PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES. | BRACCO IND CHIMICA SPA (IT) | 1990-05-02 | — | — | EP | disclosed |
| WO-1988009328-A1 | PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1988-12-01 | — | — | WO | disclosed |