Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3421288 | 0.86 | IDO1 (0.58) | TAAR1KMT2AMEN1IDO1NPC1 | |
| SCHEMBL6804590 | 0.82 | MTNR1A (0.59) | TAAR1NPC1RAB9ADRD2DRD4 | |
| SCHEMBL525787 | 0.81 | NPC1 (0.70) | TAAR1KMT2AMEN1IDO1NPC1 | |
| SCHEMBL2163818 | 0.78 | PRSS1 (0.51) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1542318 | 0.77 | PRMT1 (0.53) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1542610 | 0.77 | PRMT1 (0.53) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1542128 | 0.77 | PRMT1 (0.53) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1542411 | 0.77 | PRMT1 (0.53) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1541826 | 0.77 | PRMT1 (0.53) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1542045 | 0.77 | PRMT1 (0.53) | TAAR1KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |