Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 3/20 | 0.53 |
| ▸ | HTR1B | P28222 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL3387863 | 0.91 | MTNR1A (0.50) | MTNR1AMTNR1BSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3363396 | 0.85 | MTNR1A (0.62) | MTNR1AMTNR1BSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8768565 | 0.82 | TAAR1 (0.56) | SMN1; SMN2RAB9ANPC1DRD4DRD2 | |
| SCHEMBL1053081 | 0.81 | MTNR1A (0.69) | MTNR1AMTNR1BSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10310294 | 0.81 | MTNR1A (0.59) | MTNR1AMTNR1BSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL27771374 | 0.81 | ALDH1A1 (0.42) | MTNR1AMTNR1BSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10459746 | 0.80 | MTNR1A (0.62) | MTNR1AMTNR1BSMN1; SMN2RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL8207466 | 0.80 | MTNR1A (0.57) | MTNR1AMTNR1BSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4576541 | 0.79 | MTNR1A (0.65) | MTNR1AMTNR1BSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11305595 | 0.79 | MTNR1A (0.56) | MTNR1AMTNR1BSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107629022-B | Antibacterial synergist and preparation method and application thereof | 上海医药工业研究院 | 2024-11-12 | — | — | CN | disclosed |
| US-6689793-B2 | INHIBITORS OF NON-NUCLEOSIDE REVERSE TRANSCRIPTASE AND MULTI-DRUG RESISTANT HUMAN IMMUNODEFICIENCY VIRUS REVERSE TRANSCRIPTASE | PARKER HUGHES INSTITUTE | 2004-02-10 | — | — | US | disclosed |
| US-20020151568-A1 | Piperidinylethyl-, phenoxyethyl-, and beta-fluorophenethyl-substituted thiourea compounds with potent anti-HIV activity | PARKER HUGHES INSTITUTE | 2002-10-17 | — | — | US | disclosed |
| US-4891069-A | CATALYST FOR REDUCTION OF METAL COMPOUND BY GENERATED HYDROGEN | TECHNO INSTRUMENTS INVESTMENTS 1983 LTD. (IL) | 1990-01-02 | — | — | US | disclosed |
| US-4790912-A | ELECTROLYTICALLY-GENERATED HYDROGEN AND CATALYST CONVERT METAL SALT IN BATH TO METAL | TECHNO-INSTRUMENTS INVESTMENTS LTD. (IL) | 1988-12-13 | — | — | US | disclosed |
| US-4749449-A | PLATING ON CATALYZED THROUGH HOLE WALL IN PATTERENED CONDUCTIVE AND INSULATING LAYERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151568-A1 | Piperidinylethyl-, phenoxyethyl-, and beta-fluorophenethyl-substituted thiourea compounds with potent anti-HIV activity | SAMHD1, PNP, NUDT1 | MTNR1A 3987/4885MTNR1B 4122/4885SMN1; SMN2 3373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.