Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768624 | 0.95 | MEN1 (0.36) | ESR2ESR1MEN1KMT2AKDM4E | |
| SCHEMBL8768555 | 0.81 | CYP1A2 (0.35) | ESR2ESR1MEN1KMT2AABL1 | |
| SCHEMBL3271256 | 0.79 | ESR1 (0.42) | ESR2ESR1MEN1KMT2AKDM4E | |
| SCHEMBL508237 | 0.73 | AURKA (0.57) | ESR2KIF11AURKATPX2ESR1 | |
| SCHEMBL7561242 | 0.73 | MEN1 (0.37) | ESR2ESR1MEN1KMT2AKDM4E | |
| SCHEMBL9146048 | 0.73 | ESR2 (0.44) | ESR2KIF11AURKATPX2ESR1 | |
| SCHEMBL8542097 | 0.72 | ESR2 (0.37) | ESR2KIF11ESR1 | |
| SCHEMBL9144621 | 0.71 | ESR2 (0.42) | ESR2KIF11AURKATPX2ESR1 | |
| SCHEMBL7560691 | 0.71 | ESR2 (0.39) | ESR2KIF11ESR1 | |
| SCHEMBL75387 | 0.70 | ESR2 (0.46) | ESR2KIF11ESR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792255-A1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0638112-A1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-02-15 | — | — | EP | disclosed |