Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | BAX | Q07812 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768568 | 0.95 | ESR2 (0.39) | MEN1KMT2AKDM4EESR1ESR2 | |
| SCHEMBL8768555 | 0.85 | CYP1A2 (0.35) | MEN1KMT2AESR1ESR2CYP1A2 | |
| SCHEMBL3271256 | 0.83 | ESR1 (0.42) | MEN1KMT2AKDM4EESR1ESR2 | |
| SCHEMBL7561242 | 0.76 | MEN1 (0.37) | MEN1KMT2AKDM4EESR1ESR2 | |
| SCHEMBL75387 | 0.74 | ESR2 (0.46) | MEN1KMT2AKDM4EESR1ESR2 | |
| SCHEMBL6466370 | 0.71 | MAPT (0.34) | MEN1KMT2ALMNASLC6A2SLC6A3 | |
| SCHEMBL9578601 | 0.71 | ESR2 (0.42) | MEN1KMT2AKDM4EESR1ESR2 | |
| SCHEMBL6727211 | 0.71 | — | — | |
| SCHEMBL7563950 | 0.69 | ESR2 (0.41) | MEN1KMT2AKDM4EESR1ESR2 | |
| SCHEMBL221511 | 0.69 | MAPT (0.52) | MEN1KMT2AKDM4EESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792255-A1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0638112-A1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-02-15 | — | — | EP | disclosed |