Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.53 |
| ▸ | PPARG | P37231 | 7/20 | 0.53 |
| ▸ | PPARD | Q03181 | 4/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767730 | 0.92 | PPARA (0.46) | PPARAPPARGPPARDKDM4ETP53 | |
| SCHEMBL8923414 | 0.86 | PPARA (0.56) | PPARAPPARGPPARDS1PR4S1PR1 | |
| SCHEMBL8767593 | 0.83 | PPARA (0.67) | PPARAPPARGPPARDPLK1 | |
| SCHEMBL8925626 | 0.79 | TSHR (0.49) | PPARAPPARGPPARDKDM4ETP53 | |
| SCHEMBL8768851 | 0.78 | PPARA (0.67) | PPARAPPARGPPARDKDM4ETP53 | |
| SCHEMBL10688594 | 0.78 | PPARA (0.60) | PPARAS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL10686096 | 0.78 | PPARA (0.60) | PPARAS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL10687273 | 0.76 | PPARA (0.63) | PPARAPPARGS1PR4S1PR1S1PR3 | |
| SCHEMBL9256781 | 0.75 | HDAC1 (0.50) | SOAT1PLK1 | |
| SCHEMBL10685098 | 0.74 | KDM4E (0.72) | S1PR4S1PR1S1PR3S1PR5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |