Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768602 | 0.92 | PPARA (0.53) | PPARAPPARGPPARDSOAT1KDM4E | |
| SCHEMBL8925626 | 0.86 | TSHR (0.49) | PPARAHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL9256781 | 0.83 | HDAC1 (0.50) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL8768990 | 0.80 | PPARA (0.50) | PPARAHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL8923414 | 0.79 | PPARA (0.56) | PPARAPPARGPPARDSOAT1KDM4E | |
| SCHEMBL8767593 | 0.78 | PPARA (0.67) | PPARAPPARGPPARD | |
| SCHEMBL8768888 | 0.78 | LPAR1 (0.50) | PPARAHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL8768112 | 0.78 | PPARA (0.56) | PPARAHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL9577853 | 0.76 | TSHR (0.56) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL8856197 | 0.75 | SOAT1 (0.60) | HDAC1HDAC6HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |