Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923414 | 0.92 | PPARA (0.56) | TSHRSOAT1PPARAPPARGPPARD | |
| SCHEMBL9577853 | 0.91 | TSHR (0.56) | TSHRSOAT1GAAHTTHDAC1 | |
| SCHEMBL9577605 | 0.88 | TSHR (0.51) | TSHRSOAT1PPARAPPARGPPARD | |
| SCHEMBL9251911 | 0.88 | HDAC1 (0.53) | TSHRSOAT1GAAHTTHDAC1 | |
| SCHEMBL8767730 | 0.86 | PPARA (0.46) | TSHRSOAT1PPARAPPARGPPARD | |
| SCHEMBL8768686 | 0.86 | PPARA (0.61) | TSHRSOAT1PPARAPPARGPPARD | |
| SCHEMBL8767784 | 0.86 | PPARA (0.61) | TSHRSOAT1PPARAPPARGPPARD | |
| SCHEMBL8767727 | 0.86 | PPARA (0.61) | TSHRSOAT1PPARAPPARGPPARD | |
| SCHEMBL9261604 | 0.85 | HDAC1 (0.51) | TSHRSOAT1GAAHTTHDAC1 | |
| SCHEMBL8767679 | 0.85 | PPARA (0.59) | TSHRSOAT1PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |