SCHEMBL8768609

SCHEMBL8768609

CCOC(COCCOCCCCCCCCO)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.43
MEN1 O00255 1/20 0.43
THRB P10828 1/20 0.43
KMT2A Q03164 1/20 0.43
MAPT P10636 1/20 0.43
USP2 O75604 1/20 0.39
LPAR1 Q92633 9/20 0.36
LPAR3 Q9UBY5 9/20 0.36
LPAR2 Q9HBW0 4/20 0.36
LPAR5 Q9H1C0 4/20 0.36
LPAR6 P43657 3/20 0.36
LPAR4 Q99677 3/20 0.36
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
TSHR P16473 1/20 0.34
PRKD3 O94806 1/20 0.34
PRKCG P05129 1/20 0.34
PRKCB P05771 1/20 0.34
PRKCA P17252 1/20 0.34
PRKCH P24723 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8768920 1.00 HTT (0.43) HTTMEN1THRBKMT2AMAPT
SCHEMBL6548143 0.86 USP2 (0.41) HTTMEN1THRBKMT2AMAPT
SCHEMBL3766375 0.82 ALDH1A1 (0.46) HTTMEN1THRBKMT2AMAPT
SCHEMBL27167532 0.76 ALDH1A1 (0.48) HTTMEN1THRBKMT2AMAPT
SCHEMBL2132844 0.76 USP2 (0.36) HTTMEN1THRBKMT2AMAPT
SCHEMBL21657309 0.73 MEN1 (0.60) HTTMEN1THRBKMT2AMAPT
SCHEMBL6021998 0.73 MEN1 (0.60) HTTMEN1THRBKMT2AMAPT
SCHEMBL11251719 0.73 MEN1 (0.60) HTTMEN1THRBKMT2AMAPT
SCHEMBL14259948 0.73 TSHR (0.40) HTTMEN1THRBKMT2AMAPT
SCHEMBL6975117 0.72 USP2 (0.52) HTTMEN1THRBKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0792255-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-03 EP disclosed