Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 7/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222707 | 0.83 | TAS1R3 (0.52) | TAS1R3TAS1R1NPC1RAB9AKMT2A | |
| SCHEMBL12514129 | 0.83 | TAS1R3 (0.57) | TAS1R3TAS1R1NPC1RAB9AKMT2A | |
| SCHEMBL8638562 | 0.82 | TAS1R3 (0.51) | TAS1R3TAS1R1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL9836181 | 0.79 | TAS1R3 (0.52) | TAS1R3TAS1R1NPC1RAB9AKMT2A | |
| SCHEMBL11575925 | 0.79 | CYP1A2 (0.68) | TAS1R3TAS1R1NPC1RAB9AKMT2A | |
| SCHEMBL23792352 | 0.78 | TAS1R3 (0.51) | TAS1R3TAS1R1NPC1RAB9AKMT2A | |
| SCHEMBL8767461 | 0.78 | HSP90AA1 (0.46) | SMN1; SMN2LMNATSHRKDM4ETHRB | |
| SCHEMBL311716 | 0.78 | ADRB2 (0.60) | TAS1R3TAS1R1NPC1RAB9AKMT2A | |
| SCHEMBL30446783 | 0.78 | TAS1R3 (0.52) | TAS1R3TAS1R1NPC1RAB9AKMT2A | |
| SCHEMBL29524334 | 0.78 | TPMT (0.69) | TAS1R3TAS1R1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579833-B1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-20 | — | — | EP | disclosed |
| EP-0579833-A1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992018461-A1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-29 | — | — | WO | disclosed |