SCHEMBL8768697

SCHEMBL8768697

C=C(C)C(=O)OCC(COO)(COC(=O)C(=C)C)COC(=O)C(=C)C

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
THRB P10828 2/20 0.42
ALDH1A1 P00352 3/20 0.40
MAPK1 P28482 2/20 0.35
HIF1A Q16665 2/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57880 0.91 TSHR (0.52) TSHRTHRBALDH1A1MAPK1HIF1A
SCHEMBL9951100 0.90 ALDH1A1 (0.44) TSHRTHRBALDH1A1MAPK1HIF1A
SCHEMBL16803285 0.89 TSHR (0.50) TSHRTHRBALDH1A1MAPK1HIF1A
SCHEMBL17698929 0.87 TSHR (0.48) TSHRTHRBALDH1A1MAPK1HIF1A
SCHEMBL11440732 0.85 TSHR (0.47) TSHRTHRBALDH1A1MAPK1HIF1A
SCHEMBL11681998 0.85 TSHR (0.47) TSHRTHRBALDH1A1MAPK1HIF1A
SCHEMBL29357664 0.85 THRB (0.48) TSHRTHRBALDH1A1MAPK1HIF1A
SCHEMBL59115 0.85 THRB (0.48) TSHRTHRBALDH1A1MAPK1HIF1A
SCHEMBL9139392 0.83 TSHR (0.45) TSHRTHRBALDH1A1MAPK1HIF1A
SCHEMBL17698931 0.83 TSHR (0.45) TSHRTHRBALDH1A1MAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0546814-B1 A polyimide photosensitive cover coating agent CHISSO CORP (JP) 1997-09-17 EP disclosed
US-5326792-A Protective coatings for flexibile circuits CHISSO CORPORATION (JP) 1994-07-05 US disclosed
EP-0546814-A1 A polyimide photosensitive cover coating agent CHISSO CORPORATION (JP) 1993-06-16 EP disclosed