Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768723 | 1.00 | ACE2 (0.37) | ACE2HTTMAPTMEN1THRB | |
| SCHEMBL9361500 | 0.93 | MEN1 (0.39) | HTTMAPTMEN1THRBKMT2A | |
| SCHEMBL28782029 | 0.93 | MEN1 (0.39) | HTTMAPTMEN1THRBKMT2A | |
| SCHEMBL8781176 | 0.91 | FFAR4 (0.37) | HTTMAPTMEN1THRBKMT2A | |
| SCHEMBL27728790 | 0.85 | CNR1 (0.33) | — | |
| SCHEMBL9427113 | 0.75 | MEN1 (0.42) | HTTMAPTMEN1THRBKMT2A | |
| SCHEMBL9814222 | 0.73 | DNM1 (0.41) | HTTMAPTMEN1THRBKMT2A | |
| SCHEMBL21963320 | 0.72 | DNM1 (0.40) | HTTMEN1KMT2AUSP2FAAH | |
| SCHEMBL1551339 | 0.72 | DNM1 (0.40) | HTTMEN1KMT2AUSP2FAAH | |
| SCHEMBL9801552 | 0.70 | LMNA (0.50) | HTTMAPTMEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790977-A1 | AMINE DERIVATIVES FOR TREATMENT OF SKIN DISORDERS | Kao Corporation (JP) | 1997-08-27 | — | — | EP | disclosed |