Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636229 | 0.88 | USP2 (0.47) | USP2HTTALDH1A1SPHK1LPAR5 | |
| SCHEMBL728014 | 0.88 | USP2 (0.64) | USP2HTTALDH1A1SPHK1LPAR5 | |
| SCHEMBL2995939 | 0.88 | USP2 (0.64) | USP2HTTALDH1A1SPHK1LPAR5 | |
| SCHEMBL2987001 | 0.88 | USP2 (0.64) | USP2HTTALDH1A1SPHK1LPAR5 | |
| SCHEMBL2991718 | 0.88 | USP2 (0.64) | USP2HTTALDH1A1SPHK1LPAR5 | |
| SCHEMBL728005 | 0.88 | USP2 (0.64) | USP2HTTALDH1A1SPHK1LPAR5 | |
| SCHEMBL9056414 | 0.88 | USP2 (0.49) | USP2HTTALDH1A1SPHK1LPAR5 | |
| SCHEMBL26942167 | 0.85 | USP2 (0.60) | USP2HTTALDH1A1SPHK1LPAR5 | |
| SCHEMBL757371 | 0.85 | USP2 (0.53) | USP2HTTALDH1A1SPHK1LPAR5 | |
| SCHEMBL18296270 | 0.83 | ALDH1A1 (0.55) | USP2HTTALDH1A1SPHK1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790977-A1 | AMINE DERIVATIVES FOR TREATMENT OF SKIN DISORDERS | Kao Corporation (JP) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996015098-A1 | AMINE DERIVATIVES FOR TREATMENT OF SKIN DISORDERS | KAO CORPORATION (JP) | 1996-05-23 | — | — | WO | disclosed |