SCHEMBL8768783

SCHEMBL8768783

CC(C)(C)c1cc(C(=O)CC(=O)c2ccccc2O)cc(C(C)(C)C)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 0.55
KMT2A Q03164 9/20 0.55
NPC1 O15118 8/20 0.55
MAPT P10636 7/20 0.55
SMN1; SMN2 Q16637 5/20 0.55
HTT P42858 4/20 0.55
HPGD P15428 4/20 0.55
ALOX12 P18054 3/20 0.55
NPSR1 Q6W5P4 2/20 0.55
LMNA P02545 5/20 0.55
KDM4E B2RXH2 4/20 0.55
TSHR P16473 1/20 0.55
ALDH1A1 P00352 2/20 0.55
GAA P10253 1/20 0.55
KCNH2 Q12809 2/20 0.53
ESRRG P62508 1/20 0.50
RAB9A P51151 7/20 0.46
TP53 P04637 2/20 0.46
HSD17B10 Q99714 2/20 0.46
USP2 O75604 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL903310 0.86 LMNA (0.66) MEN1KMT2ANPC1MAPTSMN1; SMN2
SCHEMBL29664124 0.86 LMNA (0.66) MEN1KMT2ANPC1MAPTSMN1; SMN2
SCHEMBL19056879 0.82 MAPT (0.55) MEN1KMT2ANPC1MAPTSMN1; SMN2
SCHEMBL598345 0.78 MEN1 (0.69) MEN1KMT2ANPC1MAPTSMN1; SMN2
SCHEMBL29702370 0.77 MEN1 (0.74) MEN1KMT2ANPC1MAPTSMN1; SMN2
SCHEMBL1548899 0.77 MEN1 (0.74) MEN1KMT2ANPC1MAPTSMN1; SMN2
SCHEMBL7594159 0.74 NPC1 (0.71) MEN1KMT2ANPC1MAPTSMN1; SMN2
SCHEMBL10488407 0.74 LMNA (0.79) MEN1KMT2ANPC1MAPTSMN1; SMN2
SCHEMBL23334931 0.74 KDM4E (0.53) MEN1KMT2ANPC1MAPTSMN1; SMN2
SCHEMBL1603455 0.74 NPC1 (0.75) MEN1KMT2ANPC1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659738-B1 N-(Carbonyl, carbonimidoyl, carbonothioyl) sulfonamide charge control agents and toners and developers EASTMAN KODAK CO (US) 1997-09-10 EP disclosed
US-5616797-A USED IN ELECTROPHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1997-04-01 US disclosed
US-5523484-A DI- OR TRI-CARBONYL SULFONAMIDO-PHENYL COMPOUNDS AS CHARGE CONTROL AGENTS EASTMAN KODAK COMPANY (US) 1996-06-04 US disclosed
EP-0659738-A1 N-(Carbonyl, carbonimidoyl, carbonothioyl) sulfonamide charge control agents and toners and developers EASTMAN KODAK COMPANY (US) 1995-06-28 EP disclosed
US-5405727-A Electrophotography EASTMAN KODAK COMPANY (US) 1995-04-11 US disclosed
US-5385800-A A metal-free, colorless, heat resistant controllers EASTMAN KODAK COMPANY (US) 1995-01-31 US disclosed