SCHEMBL903310

SCHEMBL903310

CC(C)(C)c1ccc(C(=O)CC(=O)c2ccccc2O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.66
SMN1; SMN2 Q16637 5/20 0.66
HTT P42858 4/20 0.66
KCNH2 Q12809 1/20 0.66
NPC1 O15118 10/20 0.65
MAPT P10636 6/20 0.65
MEN1 O00255 5/20 0.65
KMT2A Q03164 5/20 0.65
HPGD P15428 4/20 0.65
ALOX12 P18054 3/20 0.65
NPSR1 Q6W5P4 2/20 0.65
RAB9A P51151 8/20 0.61
ESRRG P62508 2/20 0.58
ALDH1A1 P00352 4/20 0.56
HSD17B10 Q99714 3/20 0.56
RECQL P46063 2/20 0.56
ALOX15 P16050 2/20 0.56
MAPK1 P28482 2/20 0.56
APEX1 P27695 1/20 0.56
TDP1 Q9NUW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29664124 1.00 LMNA (0.66) LMNASMN1; SMN2HTTKCNH2NPC1
SCHEMBL8768783 0.86 MEN1 (0.55) LMNASMN1; SMN2HTTKCNH2NPC1
SCHEMBL10488407 0.84 LMNA (0.79) LMNASMN1; SMN2HTTKCNH2NPC1
SCHEMBL268855 0.83 RAB9A (0.73) LMNASMN1; SMN2HTTKCNH2NPC1
SCHEMBL450084 0.83 RAB9A (0.85) LMNASMN1; SMN2HTTKCNH2NPC1
Avobenzone SCHEMBL6129882 0.83 LMNA (0.71) LMNASMN1; SMN2HTTKCNH2NPC1
SCHEMBL8391939 0.83 NPC1 (0.63) LMNASMN1; SMN2HTTKCNH2NPC1
SCHEMBL7594159 0.82 NPC1 (0.71) LMNASMN1; SMN2HTTKCNH2NPC1
SCHEMBL23093687 0.82 LMNA (0.63) LMNASMN1; SMN2HTTKCNH2NPC1
SCHEMBL1603455 0.82 NPC1 (0.75) LMNASMN1; SMN2HTTKCNH2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023110777-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE L'OREAL (FR) 2023-06-22 WO claimed
CN-110831569-B Photoprotective compositions 欧莱雅 2022-10-21 CN claimed
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'OREAL (FR) 2022-07-21 US claimed
CN-114699328-A Photoprotective compositions 欧莱雅 2022-07-05 CN claimed
US-20200138684-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'OREAL (FR) 2020-05-07 US claimed
EP-3644954-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'Oreal (FR) 2020-05-06 EP claimed
CN-110831569-A Photoprotective composition comprising a dibenzoylmethane derivative, a merocyanine compound and a compound capable of accepting the energy of the triplet excitation level of the dibenzoylmethane compound 欧莱雅 2020-02-21 CN claimed
WO-2019002495-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'OREAL (FR) 2019-01-03 WO claimed
US-4814162-A SUNSCREENS L'OREAL (FR) 1989-03-21 US claimed
EP-3717075-B1 A BI-PHASE SUN CARE COMPOSITION OREAL (FR) 2024-10-30 EP disclosed
CN-117597102-A Sun protection W/O emulsion 莱雅公司 2024-02-23 CN disclosed
WO-2023110777-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE L'OREAL (FR) 2023-06-22 WO disclosed
US-20230040911-A1 Oil-In-Water-Type Emulsion Cosmetic L V M H RECHERCHE (FR) 2023-02-09 US disclosed
US-20230025603-A1 SUN CARE COMPOSITION L'OREAL (FR) 2023-01-26 US disclosed
US-5523484-A DI- OR TRI-CARBONYL SULFONAMIDO-PHENYL COMPOUNDS AS CHARGE CONTROL AGENTS EASTMAN KODAK COMPANY (US) 1996-06-04 US disclosed
EP-0659738-A1 N-(Carbonyl, carbonimidoyl, carbonothioyl) sulfonamide charge control agents and toners and developers EASTMAN KODAK COMPANY (US) 1995-06-28 EP disclosed
US-5405727-A Electrophotography EASTMAN KODAK COMPANY (US) 1995-04-11 US disclosed
US-5385800-A A metal-free, colorless, heat resistant controllers EASTMAN KODAK COMPANY (US) 1995-01-31 US disclosed
US-4814162-A SUNSCREENS L'OREAL (FR) 1989-03-21 US disclosed
US-4710584-A Derivatives of 3-benzylidene camphor, process for their preparation and their use as protective agents against UV rays and as medicaments L'OREAL (FR) 1987-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200138684-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND DDT, ERCC5, ERCC1 LMNA 2725/4885SMN1; SMN2 4778/4885HTT 777/4885
US-20230040911-A1 Oil-In-Water-Type Emulsion Cosmetic CUTA, PHOSPHO1, LIPE LMNA 874/4885SMN1; SMN2 4622/4885HTT 3102/4885
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND ERCC5, DDT, ERCC1 LMNA 2955/4885SMN1; SMN2 4794/4885HTT 738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.