Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.82 |
| ▸ | PPARA | Q07869 | 7/20 | 0.82 |
| ▸ | PPARD | Q03181 | 3/20 | 0.64 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.59 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768601 | 0.92 | PPARG (0.70) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL8159724 | 0.91 | PPARA (1.00) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL8160184 | 0.88 | PPARA (0.81) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL6060924 | 0.85 | PPARG (1.00) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL29376860 | 0.85 | PPARG (1.00) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL8925577 | 0.85 | PPARA (0.60) | PPARGPPARAPPARD | |
| SCHEMBL14577557 | 0.84 | PPARA (0.85) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL8925066 | 0.82 | PPARA (0.85) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL28023966 | 0.82 | PPARG (0.72) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL17471275 | 0.81 | PPARG (0.85) | PPARGPPARAPPARDSOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |