Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.60 |
| ▸ | PPARG | P37231 | 9/20 | 0.60 |
| ▸ | PPARD | Q03181 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768980 | 0.92 | PPARA (0.50) | PPARAPPARGPPARDLMNAGAA | |
| SCHEMBL6941878 | 0.91 | PPARA (0.72) | PPARAPPARGPPARDPLK1PLK3 | |
| SCHEMBL8926283 | 0.88 | PPARA (0.68) | PPARAPPARGPPARDPLK1PLK3 | |
| SCHEMBL8768153 | 0.87 | PPARA (0.58) | PPARAPPARGPPARDLMNAGAA | |
| SCHEMBL8768806 | 0.86 | PPARA (0.50) | PPARAPPARGPPARDLMNAGAA | |
| SCHEMBL8768099 | 0.85 | TSHR (0.52) | PPARAPPARGPPARDLMNAGAA | |
| SCHEMBL8768837 | 0.85 | PPARG (0.82) | PPARAPPARGPPARD | |
| SCHEMBL8767877 | 0.83 | HDAC6 (0.59) | PPARAPPARGPPARDTSHR | |
| SCHEMBL8925426 | 0.83 | PPARA (0.45) | PPARAPPARGPPARDLMNAGAA | |
| SCHEMBL8767784 | 0.82 | PPARA (0.61) | PPARAPPARGPPARDGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |