Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 7/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CYP21A2 | P08686 | 3/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767744 | 0.86 | PGR (0.32) | PGR | |
| SCHEMBL8767932 | 0.86 | — | — | |
| SCHEMBL8768855 | 0.85 | — | — | |
| SCHEMBL8768992 | 0.84 | PGR (0.32) | PGR | |
| SCHEMBL9171269 | 0.81 | CYP17A1 (0.33) | PGRCYP17A1ARCYP21A2CYP11B1 | |
| SCHEMBL9173992 | 0.79 | CYP1B1 (0.44) | PGRCYP17A1ARCYP21A2CYP11B1 | |
| SCHEMBL9177699 | 0.79 | CYP1B1 (0.44) | PGRCYP17A1ARCYP21A2CYP11B1 | |
| SCHEMBL8768194 | 0.79 | — | — | |
| SCHEMBL8767904 | 0.76 | — | — | |
| SCHEMBL8768115 | 0.76 | PGR (0.30) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567469-B1 | 14beta-H-, 14- AND 15-EN-11beta-ARYL-4-ESTRENES | SCHERING AG (DE) | 1997-08-27 | — | — | EP | disclosed |
| US-5426102-A | Antigestagenic, antiandrogenic, antiglucocorticoid, antimineralcorticoid properties | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-06-20 | — | — | US | disclosed |