Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767953 | 0.92 | PARP1 (0.31) | — | |
| SCHEMBL8768005 | 0.88 | — | — | |
| SCHEMBL8768206 | 0.87 | — | — | |
| SCHEMBL8768846 | 0.86 | — | — | |
| SCHEMBL8768906 | 0.85 | — | — | |
| SCHEMBL8653911 | 0.74 | MAPT (0.48) | ESR2ESR1 | |
| SCHEMBL8767744 | 0.74 | PGR (0.32) | — | |
| SCHEMBL8410110 | 0.73 | PGR (0.36) | — | |
| SCHEMBL5891966 | 0.73 | PGR (0.36) | — | |
| SCHEMBL8768994 | 0.71 | HSD17B1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567469-B1 | 14beta-H-, 14- AND 15-EN-11beta-ARYL-4-ESTRENES | SCHERING AG (DE) | 1997-08-27 | — | — | EP | disclosed |
| US-5426102-A | Antigestagenic, antiandrogenic, antiglucocorticoid, antimineralcorticoid properties | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-06-20 | — | — | US | disclosed |