Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.56 |
| ▸ | PPARG | P37231 | 8/20 | 0.56 |
| ▸ | PPARD | Q03181 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768153 | 0.92 | PPARA (0.58) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL8768880 | 0.84 | SOAT1 (0.51) | PPARAPPARGPPARDMAPTGAA | |
| SCHEMBL8925777 | 0.82 | PPARA (0.62) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL6941878 | 0.81 | PPARA (0.72) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL8925577 | 0.79 | PPARA (0.60) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL8926283 | 0.79 | PPARA (0.68) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL8923414 | 0.77 | PPARA (0.56) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL8768146 | 0.74 | SOAT1 (0.48) | PPARAPPARGPPARDMAPTTSHR | |
| SCHEMBL9253022 | 0.74 | PPARG (0.50) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL6359190 | 0.73 | PPARA (0.61) | PPARAPPARGPPARDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |