Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 6/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222814 | 0.80 | FDPS (0.50) | SMN1; SMN2L3MBTL1FDPSPGK1PGK2 | |
| SCHEMBL9222175 | 0.79 | FDPS (0.49) | SMN1; SMN2L3MBTL1FDPSPGK1PGK2 | |
| SCHEMBL8768063 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2L3MBTL1FDPSPGK1PGK2 | |
| SCHEMBL4183766 | 0.70 | FDPS (0.46) | SMN1; SMN2L3MBTL1FDPSPGK1PGK2 | |
| Phosphoric Acid SCHEMBL28134560 | 0.70 | L3MBTL1 (0.54) | SMN1; SMN2L3MBTL1FDPSPGK1PGK2 | |
| SCHEMBL10704341 | 0.68 | L3MBTL1 (0.57) | SMN1; SMN2L3MBTL1FDPSPGK1PGK2 | |
| SCHEMBL8049725 | 0.68 | L3MBTL1 (0.52) | SMN1; SMN2L3MBTL1FDPSPGK1PGK2 | |
| SCHEMBL21518589 | 0.68 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1FDPSPGK1PGK2 | |
| SCHEMBL27352254 | 0.68 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1FDPSPGK1PGK2 | |
| SCHEMBL30668860 | 0.68 | FDPS (0.44) | SMN1; SMN2L3MBTL1FDPSPGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639199-B1 | PREPARATION OF 2-(PYRIDYL)ETHYL SUBSTITUTED PHOSPHORUS COMPOUNDS | DU PONT (US) | 1997-08-27 | — | — | EP | disclosed |
| EP-0639199-A1 | PREPARATION OF 2-(PYRIDYL)ETHYL SUBSTITUTED PHOSPHORUS COMPOUNDS. | DU PONT (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5290935-A | Catalysts for increasing polyamide molecular weight | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-03-01 | — | — | US | disclosed |
| US-5258469-A | Catalysts for increasing the molecular weight of polyamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-11-02 | — | — | US | disclosed |
| EP-0639199-A4 | PREPARATION OF 2-(PYRIDYL)ETHYL SUBSTITUTED PHOSPHORUS COMPOUNDS. | DU PONT (US) | 1993-09-17 | — | — | EP | disclosed |
| US-5194616-A | Reacting vinylpyridine with a di- or tri-hydrocarbylphosphite in the presence of a silane, protic acid or lewis acid | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-16 | — | — | US | disclosed |
| WO-1992012985-A1 | PREPARATION OF 2-(PYRIDYL)ETHYL SUBSTITUTED PHOSPHORUS COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-06 | — | — | WO | disclosed |