Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18351233 | 0.77 | ALDH1A1 (0.47) | KDM4EHPGDLMNAEPHX1ALDH1A1 | |
| SCHEMBL4739865 | 0.77 | CCR4 (0.44) | KDM4EHPGDLMNAKMT2AEPHX1 | |
| SCHEMBL871745 | 0.77 | CDC25B (0.42) | KDM4EHPGDLMNAKMT2AL3MBTL1 | |
| SCHEMBL1605213 | 0.76 | KDM4E (0.42) | KDM4EHPGDLMNAKMT2AL3MBTL1 | |
| SCHEMBL38590 | 0.75 | CDC25B (0.50) | KDM4EHPGDLMNAKMT2AL3MBTL1 | |
| SCHEMBL2622223 | 0.74 | IDO1 (0.55) | KDM4EHPGDLMNAALDH1A1TSHR | |
| SCHEMBL31303189 | 0.74 | IDO1 (0.55) | KDM4EHPGDLMNAALDH1A1TSHR | |
| SCHEMBL3766930 | 0.74 | CDC25B (0.49) | KDM4EHPGDLMNAKMT2AL3MBTL1 | |
| SCHEMBL2234377 | 0.73 | KDM4E (0.70) | KDM4EHPGDLMNAKMT2AL3MBTL1 | |
| SCHEMBL2127595 | 0.73 | KDM4E (0.39) | KDM4EHPGDLMNAKMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734432-B1 | SYNTHETIC ESTER LUBRICANT STABILIZER COMPOSITION | GOODRICH CO B F (US) | 1997-09-03 | — | — | EP | disclosed |