SCHEMBL871745

SCHEMBL871745

CCCCCC(C)(C)c1ccccc1Nc1cccc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 3/20 0.42
CDC25A P30304 1/20 0.42
CDC25C P30307 1/20 0.42
HPGD P15428 3/20 0.41
TP53 P04637 2/20 0.41
CYP3A4 P08684 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 2/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
ATM Q13315 1/20 0.41
CCR4 P51679 6/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 1/20 0.40
KMT2A Q03164 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
EPHX1 P07099 1/20 0.39
RAB9A P51151 1/20 0.38
CNR1 P21554 2/20 0.38
CNR2 P34972 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1605213 0.99 KDM4E (0.42) CDC25BCDC25ACDC25CHPGDTP53
SCHEMBL2127595 0.85 KDM4E (0.39) HPGDALDH1A1KDM4ELMNAKMT2A
SCHEMBL27615740 0.84 CNR2 (0.40) HPGDALDH1A1KDM4ELMNAKMT2A
SCHEMBL10580580 0.84 CNR2 (0.40) HPGDALDH1A1KDM4ELMNAKMT2A
SCHEMBL30798973 0.82 CCR4 (0.47) CDC25BCDC25ACDC25CHPGDTP53
SCHEMBL9429869 0.82 CCR4 (0.47) CDC25BCDC25ACDC25CHPGDTP53
SCHEMBL30172544 0.82 CCR4 (0.47) CDC25BCDC25ACDC25CHPGDTP53
SCHEMBL38590 0.81 CDC25B (0.50) CDC25BCDC25ACDC25CHPGDTP53
SCHEMBL2128287 0.80 HTR1B (0.40) HPGDALDH1A1KDM4ELMNAKMT2A
SCHEMBL3766930 0.80 CDC25B (0.49) CDC25BCDC25ACDC25CHPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 727 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025126139-A1 LUBRICANT COMPOSITIONS CONTAINING AROMATIC AMINES FOR REDUCED ABNORMAL COMBUSTION EVENTS IN HYDROGEN FUELED ENGINES INFINEUM INTERNATIONAL LIMITED (GB) 2025-06-19 WO claimed
CN-110462010-B Ether-based lubricant compositions, methods and uses 卡斯特罗尔有限公司 2023-01-10 CN claimed
US-20200115651-A1 Ether-Based Lubricant Compositions, Methods and Uses CASTROL LIMITED (GB) 2020-04-16 US claimed
US-20200102521-A1 Ether-Based Lubricant Compositions, Methods and Uses CASTROL LIMITED (GB) 2020-04-02 US claimed
EP-3555248-A1 ETHER-BASED LUBRICANT COMPOSITIONS, METHODS AND USES Castrol Limited (GB) 2019-10-23 EP claimed
EP-3555250-A1 ETHER-BASED LUBRICANT COMPOSITIONS, METHODS AND USES Castrol Limited (GB) 2019-10-23 EP claimed
WO-2018109128-A1 ETHER-BASED LUBRICANT COMPOSITIONS, METHODS AND USES CASTROL LIMITED (GB) 2018-06-21 WO claimed
WO-2018109123-A1 ETHER-BASED LUBRICANT COMPOSITIONS, METHODS AND USES CASTROL LIMITED (GB) 2018-06-21 WO claimed
US-5336420-A Reaction product of mercaptoheterocyclic compounds with quaternary ammonium salts and hydrocarbon-substituted succinic anhydride MOBIL OIL CORPORATION (US) 1994-08-09 US claimed
US-4216100-A FRO GAS TURBINE ENGINES TEXACO INC. (US) 1980-08-05 US claimed
US-RE28805-E Lubricants containing amine antioxidants MOBIL OIL CORPORATION (US) 1976-05-11 US claimed
US-20260132352-A1 LUBRICATING OIL COMPOSITIONS INFINEUM INTERNATIONAL LTD (GB) 2026-05-14 US disclosed
EP-4596662-B1 AMINE CONTAINING POLYMERS AND LUBRICANT COMPOSITIONS INCLUDING SUCH POLYMERS AND METHODS OF USING THEREOF INFINEUM INT LTD (GB) 2026-04-29 EP disclosed
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels ExxonMobil Technology and Engineering Company (US) 2026-04-28 US disclosed
US-12606766-B2 Multipurpose oxypyridinones and their functional use-4 INFINEUM INTERNATIONAL LIMITED (US) 2026-04-21 US disclosed
US-4124514-A PENTAERYTHRITOL, CARBOXYLIC ACIDS, AMINES, ANTHRAQUINONES, PHOSPHATE ESTERS, AROMATIC SUBSTITUTED THIOPHENE TEXACO INC. (US) 1978-11-07 US disclosed
US-4124513-A PENTAERYTHRITOL, CARBOXYLIC ACIDS, AMINES, ANTHRAQUINONES, PHOSPHATE ESTERS, N-ALKYL-BENZOTHIAZOLE-2-THIONE TEXACO INC. (US) 1978-11-07 US disclosed
US-4119551-A OXIDATION RESISTANCE, NAPHTHYLPHENYLAMINES AND DIPHENYLAMINES, POLYHYDROXYANTHRAQUINONE, PHOSPHATE ESTER, BIS/DIALKYLTHIOCARBAMYL) SULFIDE TEXACO INC. (US) 1978-10-10 US disclosed
US-4096078-A LUBRICATING OILS, ESTER BASED TEXACO INC. (US) 1978-06-20 US disclosed
US-3879307-A Organic compositions containing synergistic antioxidant mixtures MOBIL OIL CORP 1975-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels TST, TCF4, MLLT1 CDC25B 2006/4885CDC25A 2020/4885CDC25C 2522/4885
US-20260132352-A1 LUBRICATING OIL COMPOSITIONS SFN, DGKG, TAF1 CDC25B 4045/4885CDC25A 3696/4885CDC25C 3223/4885
US-12606766-B2 Multipurpose oxypyridinones and their functional use-4 PHOSPHO1, SIGMAR1, SGMS1 CDC25B 2542/4885CDC25A 2451/4885CDC25C 1470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.