Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768678 | 0.90 | ACACB (0.38) | ACACBGRM5ALDH1A1KDM4EMAPT | |
| SCHEMBL8768301 | 0.88 | PTGDR2 (0.38) | ACACBGRM5ALDH1A1MAPT | |
| SCHEMBL8769345 | 0.77 | ACACB (0.39) | ACACBGRM5ALDH1A1NPC1RAB9A | |
| SCHEMBL8768691 | 0.74 | ACACB (0.35) | ACACBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL25234238 | 0.72 | PGK1 (0.35) | ALDH1A1MAPT | |
| SCHEMBL25272926 | 0.68 | HSD17B10 (0.36) | ACACBALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL8773748 | 0.68 | CYP11B1 (0.37) | ACACBGRM5 | |
| SCHEMBL8768674 | 0.67 | CLK1 (0.40) | GRM5ALDH1A1SMN1; SMN2NPC1CLK1 | |
| SCHEMBL9032513 | 0.67 | CLK4 (0.62) | ALDH1A1SMN1; SMN2MAPTTP53HSD17B10 | |
| SCHEMBL9158138 | 0.66 | CNR1 (0.54) | ALDH1A1SMN1; SMN2MAPTNPC1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579908-B1 | Pyridyl derivatives, process for their preparation and their use as pesticides | BAYER AG (DE) | 1997-09-10 | — | — | EP | disclosed |
| US-5371095-A | Fungicides, miticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |
| EP-0579908-A2 | Pyridyl derivatives, process for their preparation and their use as pesticides | BAYER AG (DE) | 1994-01-26 | — | — | EP | disclosed |