Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25272926 | 0.83 | HSD17B10 (0.36) | ALDH1A1MAPK1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL8769158 | 0.83 | PTGER2 (0.43) | CLK1HTR7ALDH1A1HPGDHTR1A | |
| SCHEMBL9399671 | 0.78 | CNR1 (0.46) | HTR7ALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL8768691 | 0.78 | ACACB (0.35) | ALDH1A1MAPK1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL23725275 | 0.77 | ALDH1A1 (0.39) | CLK1HTR7ALDH1A1HPGDHTR1A | |
| SCHEMBL8769345 | 0.76 | ACACB (0.39) | ALDH1A1MAPK1HPGDNPC1RAB9A | |
| SCHEMBL9158138 | 0.75 | CNR1 (0.54) | ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL25224130 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MAPK1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL1110998 | 0.73 | HTR7 (0.42) | CLK1HTR7HTR1ADRD2HTR2A | |
| SCHEMBL31598824 | 0.73 | HTR7 (0.47) | CLK1HTR7ALDH1A1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579908-B1 | Pyridyl derivatives, process for their preparation and their use as pesticides | BAYER AG (DE) | 1997-09-10 | — | — | EP | claimed |
| EP-0579908-A2 | Pyridyl derivatives, process for their preparation and their use as pesticides | BAYER AG (DE) | 1994-01-26 | — | — | EP | claimed |
| CN-103947645-A | 1- (pyrid-3-yl) -pyrazole and 1- (pyrimid-5-yl) -pyrazole as pesticide | BAYER CROPSCIENCE AG | 2014-07-30 | — | — | CN | disclosed |
| CN-102573478-A | 1- (pyridin-3-yl) -pyrazoles and 1- (pyrimidin-5-yl) -pyrazoles as pesticides | BAYER CROPSCIENCE AG | 2012-07-11 | — | — | CN | disclosed |
| EP-0579908-B1 | Pyridyl derivatives, process for their preparation and their use as pesticides | BAYER AG (DE) | 1997-09-10 | — | — | EP | disclosed |
| US-5434267-A | Process for the preparation of substituted 3-alkoxyacrylates | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-18 | — | — | US | disclosed |
| US-5371095-A | Fungicides, miticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |
| US-5310919-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-10 | — | — | US | disclosed |
| EP-0579908-A2 | Pyridyl derivatives, process for their preparation and their use as pesticides | BAYER AG (DE) | 1994-01-26 | — | — | EP | disclosed |
| US-5196541-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-AMINOACRYLIC ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | disclosed |
| US-5120734-A | FUNGICIDAL PYRID-2-YL-AMINO ACETIC ACID ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-09 | — | — | US | disclosed |
| US-5008275-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-16 | — | — | US | disclosed |