Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664987 | 0.89 | ECE1 (0.43) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL1667338 | 0.82 | MAOB (0.48) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL1665686 | 0.82 | MAOB (0.48) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL1663520 | 0.79 | ECE1 (0.49) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL1663515 | 0.75 | KCNK3 (0.46) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL12790839 | 0.74 | ALDH1A1 (0.47) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL13964567 | 0.74 | KMT2A (0.42) | KMT2APOLBRAB9A | |
| SCHEMBL1664919 | 0.73 | MAOB (0.46) | MAPTALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL1664465 | 0.73 | KCNK3 (0.51) | MAPTALDH1A1SMN1; SMN2KDM4EMCL1 | |
| SCHEMBL1664882 | 0.72 | SMYD3 (0.44) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068406-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2012-05-24 | — | — | WO | disclosed |