SCHEMBL8769243

SCHEMBL8769243

CCCCCCCCOC(C)(OC)OCC.O=S(=O)(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CES1 P23141 5/20 0.33
CES2 O00748 1/20 0.33
F2 P00734 2/20 0.31
PRSS1 P07477 2/20 0.31
PRSS2 P07478 2/20 0.31
PRSS3 P35030 2/20 0.31
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8769618 0.81 CES1 (0.35) CES1CES2
SCHEMBL8769246 0.76 CES1 (0.42) CES1CES2F2PRSS1PRSS2
SCHEMBL23581441 0.75 F2 (0.38) CES1CES2F2PRSS1PRSS2
SCHEMBL27824073 0.74 CES1 (0.45) CES1CES2F2PRSS1PRSS2
SCHEMBL8769249 0.72 CES1 (0.35) CES1CES2F2PRSS1PRSS2
Octadecylamine SCHEMBL19743165 0.72 DNM1 (0.43) CES1CES2F2PRSS1PRSS2
Tetrahexylammonium SCHEMBL238607 0.72 SLC22A1 (0.43) CES1EPHX1
SCHEMBL8769629 0.72 CES1 (0.35) CES1CES2F2PRSS1PRSS2
Octadecylamine SCHEMBL18546863 0.71 DNM1 (0.42) CES1F2PRSS1PRSS2PRSS3
Tetrahexylammonium SCHEMBL236770 0.71 SLC22A1 (0.42) CES1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0792255-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-03 EP disclosed