SCHEMBL8769246

SCHEMBL8769246

CCCCCCCCOCCOCCOC.O=S(=O)(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.42
CES2 O00748 5/20 0.42
MEN1 O00255 1/20 0.40
THRB P10828 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
MAPT P10636 1/20 0.40
FAAH O00519 3/20 0.34
F2 P00734 2/20 0.33
PRSS1 P07477 2/20 0.33
PRSS2 P07478 2/20 0.33
PRSS3 P35030 2/20 0.33
EPHX1 P07099 1/20 0.33
PLA2G2C Q5R387 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23581441 0.85 F2 (0.38) CES1CES2F2PRSS1PRSS2
SCHEMBL8769624 0.82 PLA2G2C (0.35) CES1CES2MEN1THRBHTT
SCHEMBL28358920 0.77 CES1 (0.37) CES1CES2MEN1KMT2AFAAH
SCHEMBL12256262 0.77 TSHR (0.36) CES1CES2MEN1THRBHTT
SCHEMBL8769249 0.76 CES1 (0.35) CES1CES2F2PRSS1PRSS2
SCHEMBL8769243 0.76 CES1 (0.33) CES1CES2F2PRSS1PRSS2
Octadecylamine SCHEMBL19743165 0.76 DNM1 (0.43) CES1CES2MEN1KMT2AFAAH
Tetrahexylammonium SCHEMBL238607 0.76 SLC22A1 (0.43) CES1EPHX1
SCHEMBL8769279 0.75 CA1 (0.41) CES1CES2MEN1THRBHTT
SCHEMBL9047614 0.75 CA1 (0.41) CES1CES2MEN1THRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0792255-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-03 EP disclosed