Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6485495 | 0.77 | NPSR1 (0.57) | NPSR1CYP2C19LMNAHTTMAPT | |
| SCHEMBL626731 | 0.77 | NPSR1 (0.57) | NPSR1CYP2C19LMNAPOLBGAA | |
| SCHEMBL11155059 | 0.72 | NPSR1 (0.54) | NPSR1CYP2C19LMNAHTTMAPT | |
| SCHEMBL7749455 | 0.72 | ALDH1A1 (0.46) | NPSR1LMNAHTTMAPTMEN1 | |
| SCHEMBL17375037 | 0.70 | ALDH1A1 (0.44) | NPSR1CYP2C19LMNAHTTMAPT | |
| SCHEMBL29739595 | 0.69 | CYP2C19 (0.56) | NPSR1CYP2C19HTTMAPTMEN1 | |
| SCHEMBL20302045 | 0.69 | NPSR1 (0.47) | NPSR1LMNAHTTMAPTMEN1 | |
| SCHEMBL23577903 | 0.69 | MEN1 (0.44) | NPSR1CYP2C19LMNAHTTMAPT | |
| SCHEMBL30183702 | 0.69 | NPSR1 (0.53) | NPSR1CYP2C19LMNAMAPTMEN1 | |
| SCHEMBL23578335 | 0.69 | NPSR1 (0.53) | NPSR1CYP2C19LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610384-B1 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS | ABBOTT LAB (US) | 1997-09-03 | — | — | EP | disclosed |