Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545362 | 0.84 | CYP1A2 (0.30) | TDP1CYP1A2LMNA | |
| SCHEMBL8768659 | 0.79 | KDM4E (0.35) | TDP1CYP1A2LMNA | |
| SCHEMBL7991493 | 0.78 | ADORA2A (0.33) | CYP1A2BTKLMNANOTUM | |
| SCHEMBL11967282 | 0.72 | TDP1 (0.37) | TDP1CYP1A2LMNAGSK3AGSK3B | |
| SCHEMBL14505514 | 0.69 | DHODH (0.35) | LMNAGSK3AGSK3B | |
| SCHEMBL7799615 | 0.69 | LMNA (0.35) | TDP1BTKLMNA | |
| SCHEMBL3520507 | 0.69 | — | — | |
| SCHEMBL8812571 | 0.68 | ALDH1A1 (0.37) | TDP1CYP1A2LMNA | |
| SCHEMBL23863066 | 0.67 | — | — | |
| SCHEMBL8604420 | 0.67 | KDM4E (0.41) | TDP1CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557907-B | 2,4, 5-Trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-115557907-A | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-110023302-B | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2022-07-26 | — | — | CN | disclosed |
| EP-0703224-B1 | Process for the preparation of alkoxytriazolinones | BAYER AG (DE) | 1997-09-03 | — | — | EP | disclosed |
| US-5606070-A | Process for the preparation of alkoxytriazolinones | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-25 | — | — | US | disclosed |
| EP-0703224-A1 | Process for the preparation of alkoxytriazolinones | BAYER AG (DE) | 1996-03-27 | — | — | EP | disclosed |