Bicarbonate

Bicarbonate

SCHEMBL8769341

N.N.O=C(O)O.O=C(O)OCO

nearest known ligand 0.33

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Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL1988403 0.97
Ammonia Solution, Strong SCHEMBL2084099 0.97 OR51E2 (0.30)
Bicarbonate SCHEMBL8356942 0.97 CA1 (0.36) CA1CA2CA9
SCHEMBL935873 0.93
Ethylene SCHEMBL465192 0.87
Ammonia Solution, Strong SCHEMBL9789241 0.81
Ammonia Solution, Strong SCHEMBL5487461 0.72 ALDH1A1 (0.33)
SCHEMBL5933492 0.72
Bicarbonate SCHEMBL26925127 0.72 CA1 (0.39) CA1CA2CA9
Bicarbonate SCHEMBL177964 0.72 CA1 (0.39) CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0618346-B1 Placing a scale inhibitor within a brine-containing subterranean formation SHELL INT RESEARCH (NL) 1997-07-23 EP disclosed
EP-0618346-A2 Placing a scale inhibitor within a brine-containing subterranean formation SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1994-10-05 EP disclosed
US-5346010-A Precipitation of scale inhibitors in subterranean formations SHELL OIL COMPANY (US) 1994-09-13 US disclosed
US-5211237-A Precipitation of scale inhibitors SHELL OIL COMPANY (US) 1993-05-18 US disclosed