Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20649 | 0.96 | ALDH1A1 (0.35) | CA1CA2CA9ALDH1A1TSHR | |
| Bicarbonate SCHEMBL1169966 | 0.93 | TSHR (0.36) | CA1CA2CA9ALDH1A1TSHR | |
| Water SCHEMBL2471732 | 0.92 | ALDH1A1 (0.33) | ALDH1A1TSHRTP53HIF1ATDP1 | |
| Ammonia Solution, Strong SCHEMBL5487461 | 0.92 | ALDH1A1 (0.33) | ALDH1A1TSHRTP53HIF1ATDP1 | |
| Benzene SCHEMBL11037140 | 0.89 | TDP1 (0.42) | ALDH1A1TSHRTP53HIF1ATDP1 | |
| Methyl Alcohol SCHEMBL1326721 | 0.89 | ALDH1A1 (0.38) | ALDH1A1TSHRTP53HIF1ATDP1 | |
| Hydrazine SCHEMBL10344909 | 0.89 | TSHR (0.33) | ALDH1A1TSHRTP53HIF1ATDP1 | |
| Ethylene SCHEMBL8927826 | 0.89 | TSHR (0.38) | ALDH1A1TSHRTP53HIF1ATDP1 | |
| Carbamic Acid SCHEMBL5450545 | 0.86 | ACHE (0.47) | ALDH1A1TSHRTP53HIF1ATDP1 | |
| Methoxymethane SCHEMBL5955384 | 0.86 | ALDH1A1 (0.36) | ALDH1A1TSHRTP53HIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 505 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118198272-A | Lithium metal electrode and lithium metal battery | 合肥国轩高科动力能源有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-115710246-A | Method for synthesizing vinylene carbonate | 无锡威孚环保催化剂有限公司 | 2023-02-24 | — | — | CN | claimed |
| CN-112961871-A | Recombinant plasmid, genetic engineering bacterium containing recombinant plasmid and application of recombinant plasmid in preparation of dimethyl carbonate | 源创核新(北京)新材料科技有限公司 | 2021-06-15 | — | — | CN | claimed |
| CN-110165297-A | A kind of procedure parameter selection method of film lithium cell solid electrolyte | 重庆市科学技术研究院 | 2019-08-23 | — | — | CN | claimed |
| US-20170338471-A1 | HIGH CAPACITY AND STABLE CATHODE MATERIALS | BATTELLE MEMORIAL INSTITUTE | 2017-11-23 | — | — | US | claimed |
| CN-103647107-B | For the dielectric film and preparation method thereof of all-solid lithium-ion battery | DONGFANG ELECTRIC CORPORATION (CN) | 2016-02-03 | — | — | CN | claimed |
| CN-104157908-A | Lithium salt electrolyte, preparation method and application thereof | UNIV XIAMEN | 2014-11-19 | — | — | CN | claimed |
| EP-2206189-B1 | NON-AQUEOUS ELECTROLYTE LITHIUM SECONDARY BATTERY | LG CHEMICAL LTD (KR) | 2014-10-22 | — | — | EP | claimed |
| EP-0482287-B2 | A non-aqueous secondary electrochemical battery | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2004-09-01 | — | — | EP | claimed |
| EP-0846346-A4 | BLENDED POLYMER GEL ELECTROLYTES | MOTOROLA INC (US) | 2001-08-22 | — | — | EP | claimed |
| EP-0846346-A1 | BLENDED POLYMER GEL ELECTROLYTES | MOTOROLA, INC. (US) | 1998-06-10 | — | — | EP | claimed |
| US-5658685-A | LIQUID ELECTROLYTE OF ALKALI METAL SALT IN SOLVENT, TWO-PHASE POLYMER BLEND GEL ELECTROLYTE SUPPORT STRUCTURE | MOTOROLA, INC. (US) | 1997-08-19 | — | — | US | claimed |
| EP-0482287-B1 | A non-aqueous secondary electrochemical battery | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1997-08-13 | — | — | EP | claimed |
| US-5639573-A | Polymer gel electrolyte | MOTOROLA, INC. (US) | 1997-06-17 | — | — | US | claimed |
| WO-1997008765-A1 | BLENDED POLYMER GEL ELECTROLYTES | MOTOROLA INC. (US) | 1997-03-06 | — | — | WO | claimed |
| US-5525443-A | COMPRISING COMPLEX OXIDE CONTAINING LITHIUM AS CATHODE, CARBON ANODE, NONAQUEOUS ELECTROLYTE CONSISTING OF INORGANIC SALT DISSOLVED IN MIXTURE OF CYCLIC ESTER AND CHAIN ESTER | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1996-06-11 | — | — | US | claimed |
| EP-0482287-A1 | A non-aqueous secondary electrochemical battery | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1992-04-29 | — | — | EP | claimed |
| CN-118335953-A | Self-supporting three-dimensional lithium alloy electrode and preparation method thereof | 合肥国轩高科动力能源有限公司 | 2024-07-12 | — | — | CN | disclosed |
| EP-0149133-A2 | Polyacetylene composite, process for production thereof, and method for use thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1985-07-24 | — | — | EP | disclosed |
| US-4416694-A | ALKYLENE CARBONATE, ATTRITION, DRYING | FOSECO INTERNATIONAL LIMITED (GB) | 1983-11-22 | — | — | US | disclosed |