Hydrazinecarboxamide

Hydrazinecarboxamide

SCHEMBL8769581

NNC(N)=O.O=P(O)(O)O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Hydrazinecarboxamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.71
NFKB1 P19838 2/20 0.71
CYP1A2 P05177 1/20 0.71
MAOA P21397 1/20 0.71
MAOB P27338 1/20 0.71
THPO P40225 1/20 0.71
LMNA P02545 3/20 0.67
CA5A P35218 3/20 0.41
CYP3A4 P08684 2/20 0.41
BLM P54132 2/20 0.41
PMP22 Q01453 2/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
CA4 P22748 3/20 0.38
KDM4E B2RXH2 1/20 0.35
KDM5C P41229 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
ALDH1A1 P00352 2/20 0.33
HIF1A Q16665 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazinecarboxamide SCHEMBL825553 1.00 TSHR (0.71) TSHRNFKB1CYP1A2MAOAMAOB
Hydrazinecarboxamide SCHEMBL27656986 0.97 LMNA (0.73) TSHRNFKB1CYP1A2MAOAMAOB
Hydrazinecarboxamide SCHEMBL27556772 0.97 TSHR (0.67) TSHRNFKB1CYP1A2MAOAMAOB
Hydrazinecarboxamide SCHEMBL2192035 0.97 TSHR (0.67) TSHRNFKB1CYP1A2MAOAMAOB
Hydrazinecarboxamide SCHEMBL7791539 0.88 TSHR (0.56) TSHRNFKB1CYP1A2MAOAMAOB
Hydrazinecarboxamide SCHEMBL11526612 0.88 TSHR (0.56) TSHRNFKB1CYP1A2MAOAMAOB
Hydrazinecarboxamide SCHEMBL15393 0.84
Hydrazinecarboxamide SCHEMBL18613867 0.84 TSHR (1.00) TSHRNFKB1CYP1A2MAOAMAOB
Hydrazinecarboxamide SCHEMBL10947599 0.84 TSHR (0.50) TSHRNFKB1CYP1A2MAOAMAOB
Hydrazinecarboxamide SCHEMBL8014908 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108380035-A A kind of formaldehyde catching fumicants and preparation method thereof 福建工程学院 2018-08-10 CN claimed
CN-102584412-A Biological organic-inorganic mixed fertilizer HENAN NONGFEI BIOLOG TECHNOLOGY CO LTD 2012-07-18 CN claimed
EP-0688852-B1 Intumescent impregnation agent WOLMAN GMBH DR (DE) 1997-09-17 EP claimed
EP-0585210-A1 Herbicidal compositions MONSANTO COMPANY (US) 1994-03-02 EP claimed
EP-0407045-A1 Safe sodium percarbonate composition TOKAI DENKA KOGYO KABUSHIKI KAISHA (JP) 1991-01-09 EP claimed
CN-218795908-U Neutralization tank for efficient mixing 四川省什邡金大化工有限公司 2023-04-07 CN disclosed
CN-115214208-A Flame-retardant wood and preparation method thereof 上海理迪道具有限公司 2022-10-21 CN disclosed
CN-108380035-A A kind of formaldehyde catching fumicants and preparation method thereof 福建工程学院 2018-08-10 CN disclosed
CN-105968711-A Acid-alkali-resistant insulated power cable material for ocean ships 梁方英 2016-09-28 CN disclosed
CN-103570420-A Nitrogenous fertilizer SHI BOBO 2014-02-12 CN disclosed
CN-102584412-A Biological organic-inorganic mixed fertilizer HENAN NONGFEI BIOLOG TECHNOLOGY CO LTD 2012-07-18 CN disclosed
EP-0407045-A1 Safe sodium percarbonate composition TOKAI DENKA KOGYO KABUSHIKI KAISHA (JP) 1991-01-09 EP disclosed
EP-0132354-B1 DEVELOPING COMPOSITION FOR LIGHT-SENSITIVE QUINONE B DIAZIDE EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-02-07 EP disclosed
EP-0132354-A2 Developing composition for light-sensitive quinone B diazide EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-01-30 EP disclosed
US-4464461-A QUATERNARY ALKANOL AMMONIUM HYDROXIDE DEVELOPER AND A SEMICARBIZIDE STABILIZER EASTMAN KODAK COMPANY (US) 1984-08-07 US disclosed