SCHEMBL8769730

SCHEMBL8769730

CC(=O)N[C@@H](Cc1ccccc1)C[C@H](O)[C@@H](N)Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 4/20 0.49
CTSS P25774 1/20 0.47
CTSK P43235 1/20 0.47
CSNK1E P49674 1/20 0.47
ALPI P09923 1/20 0.46
PKM P14618 1/20 0.46
PTGS1 P23219 1/20 0.46
XIAP P98170 1/20 0.46
SLC7A5 Q01650 1/20 0.46
LAP3 P28838 2/20 0.45
ANPEP P15144 1/20 0.45
RNPEP Q9H4A4 1/20 0.45
DNPEP Q9ULA0 1/20 0.45
CTSC P53634 1/20 0.45
LMNA P02545 1/20 0.44
SLC15A1 P46059 1/20 0.44
LTA4H P09960 1/20 0.44
PAM P19021 1/20 0.44
REN P00797 2/20 0.44
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3805270 0.88 SLC15A1 (0.47) CTRB1CSNK1EALPIPKMPTGS1
SCHEMBL13535103 0.86 SLC15A1 (0.44) CTRB1CSNK1EALPIPKMPTGS1
SCHEMBL3742163 0.82 SLC7A5 (0.44) SLC7A5LAP3SLC15A1LTA4HREN
SCHEMBL8909987 0.82 ATM (0.61) CTSSCTSKCYP3A4
SCHEMBL31506428 0.82 ATM (0.61) CTSSCTSKCYP3A4
SCHEMBL8910000 0.82 ATM (0.61) CTSSCTSKCYP3A4
SCHEMBL5541452 0.82 ATM (0.61) CTSSCTSKCYP3A4
SCHEMBL2059435 0.82 ATM (0.61) CTSSCTSKCYP3A4
SCHEMBL22305235 0.82 ATM (0.61) CTSSCTSKCYP3A4
SCHEMBL7347831 0.82 ATM (0.61) CTSSCTSKCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0672649-B1 Process for producing optically active diaminohexanone derivative TAKASAGO PERFUMERY CO LTD (JP) 1997-09-17 EP disclosed
US-5523458-A HYDROGENATION OF (2S)-2,5-DIAMINO-1,6-DIPHENYL-4-HEXENE-3-ONE USING TRANSITION METAL COMPOUNDS AS CATALYSTS TAKASAGO INTERNATIONAL CORPORATION (JP) 1996-06-04 US disclosed
EP-0672649-A1 Process for producing optically active diaminohexanone derivative Takasago International Corporation (JP) 1995-09-20 EP disclosed