Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 10/20 | 0.48 |
| ▸ | AR | P10275 | 9/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769771 | 0.83 | PGR (0.59) | PGRARNR3C1CYP3A4MAPT | |
| SCHEMBL8769023 | 0.81 | PGR (0.67) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL8769115 | 0.81 | PGR (0.52) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL8769113 | 0.81 | PGR (0.48) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL20266962 | 0.80 | PGR (0.67) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL10952461 | 0.80 | PGR (0.67) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL12904792 | 0.77 | AR (0.45) | PGRARCYP3A4CYP2C19CYP19A1 | |
| SCHEMBL12942811 | 0.77 | PGR (0.50) | PGRARNR3C1PDE4DCHRM2 | |
| SCHEMBL3762688 | 0.77 | PGR (0.40) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL924267 | 0.77 | PGR (0.40) | PGRARNR3C1PDE4DCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785211-A1 | New substituted 19-nor-pregnane derivatives | LABORATOIRE THERAMEX (MC) | 1997-07-23 | — | — | EP | disclosed |