Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 11/20 | 0.67 |
| ▸ | AR | P10275 | 10/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769794 | 0.81 | PGR (0.48) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL8769119 | 0.81 | PGR (0.72) | PGRARNR3C1PDE4DCYP3A4 | |
| Nomegestrol Acetate SCHEMBL8817628 | 0.80 | PGR (1.00) | PGRARNR3C1PDE4DCYP3A4 | |
| Nomegestrol Acetate SCHEMBL19760877 | 0.80 | PGR (1.00) | PGRARNR3C1PDE4DCYP3A4 | |
| Nomegestrol Acetate SCHEMBL37517 | 0.80 | PGR (1.00) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL8769771 | 0.79 | PGR (0.59) | PGRARNR3C1CYP3A4LMNA | |
| SCHEMBL8769481 | 0.79 | PGR (0.48) | PGRARNR3C1PDE4DCYP3A4 | |
| SCHEMBL8769113 | 0.77 | PGR (0.48) | PGRARNR3C1PDE4DCYP3A4 | |
| Nomegestrol SCHEMBL19760878 | 0.75 | LMNA (0.80) | PGRARNR3C1PDE4DCYP3A4 | |
| Nomegestrol SCHEMBL139763 | 0.75 | LMNA (0.80) | PGRARNR3C1PDE4DCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027209-A1 | NEW SUBSTITUTED 19-NOR-PREGNANE DERIVATIVES | LABORATOIRE THERAMEX (MC) | 1997-07-31 | — | — | WO | disclosed |
| EP-0785211-A1 | New substituted 19-nor-pregnane derivatives | LABORATOIRE THERAMEX (MC) | 1997-07-23 | — | — | EP | disclosed |