Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.57 |
| ▸ | CTSL | P07711 | 9/20 | 0.46 |
| ▸ | CTSB | P07858 | 8/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4202065 | 0.79 | CTRB1 (0.62) | CTRB1CTSLCTSBCTSSCTSK | |
| SCHEMBL7361852 | 0.77 | CTRB1 (0.64) | CTRB1CTSLCTSBCTSSCTSK | |
| SCHEMBL7361850 | 0.77 | CTRB1 (0.64) | CTRB1CTSLCTSBCTSSCTSK | |
| SCHEMBL26745215 | 0.76 | GAA (0.55) | NPC1GAAMAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL2435512 | 0.75 | CTRB1 (0.76) | CTRB1CTSLCTSBCTSSCTSK | |
| SCHEMBL2482903 | 0.75 | CTRB1 (0.76) | CTRB1CTSLCTSBCTSSCTSK | |
| SCHEMBL1051352 | 0.75 | CTRB1 (0.76) | CTRB1CTSLCTSBCTSSCTSK | |
| SCHEMBL7398976 | 0.74 | CTRB1 (0.60) | CTRB1CTSLCTSBCTSSCTSK | |
| SCHEMBL7398974 | 0.74 | CTRB1 (0.60) | CTRB1CTSLCTSBCTSSCTSK | |
| SCHEMBL14069202 | 0.74 | CTRB1 (0.60) | CTRB1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793673-A1 | ALPHA-KETOAMIDE DERIVATIVES AS CATHEPSIN L INHIBITOR | Takeda Chemical Industries, Ltd. (JP) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996016079-A2 | ALPHA-KETOAMIDE DERIVATIVES AS CATHEPSIN L INHIBITOR | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1996-05-30 | — | — | WO | disclosed |