SCHEMBL8769905

SCHEMBL8769905

C[Si](C)(C)C(C(N)=O)(C(=O)O)[Si](C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
ACHE P22303 1/20 0.32
LMNA P02545 1/20 0.30
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL450803 0.82 TSHR (0.39) ALDH1A1TSHR
Hydrochloric Acid SCHEMBL4533593 0.80 LMNA (0.32) LMNAALOX15BLMPMP22MAPT
SCHEMBL3299583 0.69 TET2 (0.32)
SCHEMBL27488352 0.67 GAA (0.30) LMNAALOX15BLMPMP22MAPT
SCHEMBL31215317 0.65
SCHEMBL10797506 0.65 LMNA (0.33) ALDH1A1LMNAALOX15BLMPMP22
SCHEMBL14938351 0.65
SCHEMBL17065142 0.65 LMNA (0.33) LMNAALOX15BLMPMP22MAPT
SCHEMBL5709616 0.65
SCHEMBL29272757 0.63 TSHR (0.39) ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0793666-A1 SILYLATION PROCESS BIOCHEMIE GESELLSCHAFT M.B.H. (AT) 1997-09-10 EP claimed
WO-1996016067-A1 SILYLATION PROCESS BIOCHEMIE GESELLSCHAFT M.B.H. (AT) 1996-05-30 WO claimed
EP-0793666-A1 SILYLATION PROCESS BIOCHEMIE GESELLSCHAFT M.B.H. (AT) 1997-09-10 EP disclosed
WO-1996016067-A1 SILYLATION PROCESS BIOCHEMIE GESELLSCHAFT M.B.H. (AT) 1996-05-30 WO disclosed