Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769898 | 0.94 | LMNA (0.35) | LMNAALOX15BLMPMP22 | |
| SCHEMBL8769905 | 0.80 | ALDH1A1 (0.32) | LMNAALOX15BLMPMP22MAPT | |
| Hydrochloric Acid SCHEMBL4542779 | 0.76 | MAPT (0.32) | MAPTKMT2A | |
| SCHEMBL3644588 | 0.73 | — | — | |
| SCHEMBL27488352 | 0.69 | GAA (0.30) | LMNAALOX15BLMPMP22MAPT | |
| SCHEMBL10797506 | 0.67 | LMNA (0.33) | LMNAALOX15BLMPMP22MAPT | |
| SCHEMBL17065142 | 0.67 | LMNA (0.33) | LMNAALOX15BLMPMP22MAPT | |
| SCHEMBL450803 | 0.65 | TSHR (0.39) | — | |
| SCHEMBL10897429 | 0.65 | LMNA (0.32) | LMNAALOX15BLMPMP22 | |
| Hydrochloric Acid SCHEMBL4541823 | 0.61 | MAPT (0.37) | LMNAALOX15BLMPMP22MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013047891-A2 | WASHING METHOD, ADDITION POLYMERIZATION METHOD, PREPOLYMERIZATION METHOD, PREPOLYMERIZED CATALYTIC COMPONENT FOR ADDITION POLYMERIZATION, AND METHOD FOR PRODUCING ADDITION POLYMER USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-04-04 | — | — | WO | disclosed |
| WO-2012118233-A1 | ADDITION POLYMERIZATION METHOD, PREPOLYMERIZED CATALYTIC COMPONENT FOR ADDITION POLYMERIZATION, AND METHOD FOR PRODUCING ADDITION POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-07 | — | — | WO | disclosed |
| WO-2012063972-A1 | METHOD FOR COATING REACTOR | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-18 | — | — | WO | disclosed |