Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TK2 | O00142 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hept SCHEMBL384288 | 0.89 | UPP1 (0.48) | UPP1TSHRMAPK1NPSR1MEN1 | |
| SCHEMBL7215341 | 0.84 | ALDH1A1 (0.44) | TSHRMAPK1NPSR1MEN1KMT2A | |
| SCHEMBL2036799 | 0.81 | UPP1 (0.39) | UPP1TSHRMAPK1NPSR1MEN1 | |
| Hept SCHEMBL1732034 | 0.80 | UPP1 (0.40) | UPP1TSHRMAPK1NPSR1MEN1 | |
| SCHEMBL7218800 | 0.79 | ALDH1A1 (0.38) | TSHRMAPK1NPSR1MEN1KMT2A | |
| SCHEMBL2789609 | 0.79 | UPP1 (0.40) | UPP1TSHRALDH1A1HPGD | |
| SCHEMBL7213302 | 0.78 | MAPK1 (0.44) | TSHRMAPK1NPSR1MEN1KMT2A | |
| SCHEMBL7015162 | 0.77 | ALDH1A1 (0.58) | UPP1TSHRMAPK1NPSR1MEN1 | |
| SCHEMBL9353768 | 0.77 | UPP1 (0.39) | UPP1 | |
| SCHEMBL9357959 | 0.77 | UPP1 (0.39) | UPP1TSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794793-A1 | COMPOSITION FOR PREVENTION AND TREATMENT OF HIV-1 INFECTION COMPRISING AT LEAST TWO DIFFERENT HIV-1 REVERSE TRANSCRIPTASE INHIBITORS | REGA INSTITUTE (BE) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996016675-A2 | COMPOSITION FOR PREVENTION AND TREATMENT OF HIV-1 INFECTION COMPRISING AT LEAST TWO DIFFERENT HIV-1 REVERSE TRANSCRIPTASE INHIBITORS | REGA INSTITUTE (BE) | 1996-06-06 | — | — | WO | disclosed |