Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015162 | 0.86 | ALDH1A1 (0.58) | MAPK1NPSR1TSHRALDH1A1HPGD | |
| Hept SCHEMBL384288 | 0.84 | UPP1 (0.48) | MAPK1NPSR1TSHRALDH1A1HPGD | |
| SCHEMBL7219920 | 0.83 | ALDH1A1 (0.52) | MAPK1NPSR1TSHRALDH1A1HPGD | |
| SCHEMBL7218800 | 0.82 | ALDH1A1 (0.38) | MAPK1NPSR1TSHRALDH1A1HPGD | |
| SCHEMBL7260700 | 0.82 | ALDH1A1 (0.36) | MAPK1NPSR1TSHRALDH1A1HPGD | |
| SCHEMBL7260701 | 0.82 | LMNA (0.37) | MAPK1NPSR1TSHRALDH1A1HPGD | |
| SCHEMBL9357368 | 0.81 | ALDH1A1 (0.35) | MAPK1NPSR1TSHRALDH1A1HPGD | |
| SCHEMBL7219572 | 0.80 | ALDH1A1 (0.39) | MAPK1NPSR1TSHRALDH1A1HPGD | |
| SCHEMBL7215341 | 0.78 | ALDH1A1 (0.44) | MAPK1NPSR1TSHRALDH1A1HPGD | |
| SCHEMBL8770174 | 0.78 | UPP1 (0.42) | MAPK1NPSR1TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37979-E1 | Pyrimidine derivatives and anti-viral agent containing the same as active ingredient thereof | MITSUBISHI CHEMICAL CORPORATION | 2003-02-04 | — | — | US | disclosed |
| EP-0829476-B1 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | MITSUBISHI CHEM CORP (JP) | 2002-08-28 | — | — | EP | disclosed |
| EP-0829476-A2 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | Mitsubishi Chemical Corporation (JP) | 1998-03-18 | — | — | EP | disclosed |
| US-5461060-A | Antiretroviral activity | MITSUBISHI KASEI CORPORATION (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0420763-A2 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | Mitsubishi Chemical Corporation (JP) | 1991-04-03 | — | — | EP | disclosed |