SCHEMBL8770232

SCHEMBL8770232

CCCCCCCCC(Oc1ccc(C(=O)c2ccccc2)cc1)c1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 2/20 0.52
SLC7A5 Q01650 3/20 0.50
ELANE P08246 3/20 0.47
SRD5A2 P31213 1/20 0.46
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
GCGR P47871 4/20 0.43
ALDH1A1 P00352 1/20 0.43
PLA2G4B P0C869 1/20 0.43
CTRC Q99895 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8371946 0.85 ELANE (0.50) ELANESRD5A2TP53TSHRALDH1A1
SCHEMBL8375161 0.85 ELANE (0.50) ELANESRD5A2TP53TSHRALDH1A1
SCHEMBL7611800 0.85 ELANE (0.50) ELANESRD5A2TP53TSHRALDH1A1
SCHEMBL8925288 0.84 ELANE (0.49) ELANESRD5A2TP53TSHRALDH1A1
SCHEMBL27868074 0.84 ELANE (0.49) ELANESRD5A2TP53TSHRALDH1A1
SCHEMBL28629364 0.84 ALDH1A1 (0.51) ELANESRD5A2TP53TSHRALDH1A1
SCHEMBL18264279 0.84 ELANE (0.49) ELANESRD5A2TP53TSHRALDH1A1
SCHEMBL9325710 0.82 TP53 (0.70) TP53TSHRPLA2G4B
SCHEMBL1765239 0.82 TP53 (0.51) SLC7A5TP53TSHRPLA2G4B
SCHEMBL11463310 0.82 TSHR (0.50) SLC7A5TP53TSHRPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5688436-A Optically anisotropic material, process for producing it, and retardation plate and liquid crystal display device using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-11-18 US disclosed
EP-0617111-B1 Optically anisotropic material, process for producing it, and retardation plate and liquid crystal display device using same SUMITOMO CHEMICAL CO (JP) 1997-09-17 EP disclosed
EP-0617111-A1 Optically anisotropic material, process for producing it, and retardation plate and liquid crystal display device using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-09-28 EP disclosed