Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770316 | 0.93 | ALDH1A1 (0.41) | ALDH1A1TSHRMEN1GAAKMT2A | |
| SCHEMBL6339548 | 0.81 | MEN1 (0.39) | ALDH1A1TSHRMEN1GAAKMT2A | |
| SCHEMBL31604 | 0.81 | CHRM1 (0.43) | MEN1GAAKMT2ANOS1NOS3 | |
| SCHEMBL3328503 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRBNOS1NOS3 | |
| SCHEMBL27343844 | 0.78 | CA2 (0.48) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL7804092 | 0.78 | CA2 (0.48) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL2443136 | 0.77 | KMT2A (0.44) | ALDH1A1MEN1GAAKMT2ANOS1 | |
| SCHEMBL2443141 | 0.77 | KMT2A (0.44) | ALDH1A1MEN1GAAKMT2ANOS1 | |
| SCHEMBL1344808 | 0.77 | KMT2A (0.39) | MEN1GAAKMT2ANOS1NOS3 | |
| SCHEMBL28710632 | 0.77 | KMT2A (0.39) | MEN1GAAKMT2ANOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |